{"id":64447,"date":"2024-06-25T14:31:05","date_gmt":"2024-06-25T04:31:05","guid":{"rendered":"https:\/\/hudson.org.au?post_type=hdsn_news_post&#038;p=64447"},"modified":"2024-06-25T14:31:07","modified_gmt":"2024-06-25T04:31:07","slug":"setting-a-new-pace-for-hypertension","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/setting-a-new-pace-for-hypertension\/","title":{"rendered":"Setting a new PACE for hypertension"},"content":{"rendered":"\n<p class=\"has-medium-font-size\">Some quick mathematics paints a disturbing picture<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"has-medium-font-size\">Six million Australians \u2013 one in three adults &#8211; have <a href=\"https:\/\/hudson.org.au\/disease\/hormones-and-health\/endocrine-hypertension\/\">hypertension<\/a><\/li>\n\n\n\n<li class=\"has-medium-font-size\">1.3 billion people worldwide, one in four adults, have hypertension<\/li>\n<\/ul>\n\n\n\n<p class=\"has-medium-font-size\">For 10 per cent of people with hypertension, the cause is a hormonal condition called primary aldosteronism (PA). Yet, only one percent of those are tested for PA.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-personal-and-professional-motivation\">Personal and professional motivation <\/h2>\n\n\n\n<p>For <a href=\"https:\/\/hudson.org.au\/researcher-profile\/jun-yang\/\">Associate Professor Jun Yang<\/a>, this issue is personal as well as professional. An endocrinologist and a researcher, soon after A\/Prof Yang started researching PA, she found that not just one, but both of her parents had the condition, which explained their inability to keep their blood pressure under control.<\/p>\n\n\n\n    <div class=\"block--callout flex z-20 text-blue-800 bg-gray-100 p-6 mb-5 sm:mb-8 sm:float-right sm:w-1\/2 sm:ml-6\">\n        <div class=\"cms-content\">\n            <h2 id=\"key-points\">Key points<\/h2>\n<ul>\n<li>Primary aldosteronism (PA) affects 10 per cent of hypertensive individuals but is often undiagnosed, impacting cardiovascular health worldwide.<\/li>\n<li>Associate Professor Jun Yang is establishing the Primary Aldosteronism Centre of Research Excellence (PACE) at Hudson Institute, aiming to improve diagnosis and treatment globally.<\/li>\n<li>PA research and treatment innovation at Hudson Institute include the CONSEP trial and groundbreaking research on PA prevalence, screening methods, and its implications for diverse populations.<\/li>\n<\/ul>\n        <\/div>\n    <\/div>\n\n    \n\n\n<p>\u201cWhat I love about PA is that it is easily detected (with the correct blood test) and has effective treatment or even a cure,\u201d A\/Prof Yang said.<\/p>\n\n\n\n<p>\u201cIt is just there, right under our noses, and yet it is often missed. If we can systematically improve its diagnosis in the whole population, we may be able to prevent many unnecessary heart attacks, strokes and kidney failure.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-the-primary-aldosteronism-centre-of-research-excellence-pace\">The Primary Aldosteronism Centre of Research Excellence (PACE)<\/h2>\n\n\n\n<p>With her mentor, <a href=\"https:\/\/hudson.org.au\/researcher-profile\/peter-fuller\/\">Professor Peter Fuller<\/a>, who is Head of Endocrinology at Monash Health and leads Hudson Institute\u2019s <a href=\"https:\/\/hudson.org.au\/research-centre\/centre-for-endocrinology-and-metabolism\/\">Centre for Endocrinology and Metabolism<\/a>, A\/Prof Yang successfully applied for an NHMRC Centre of Research Excellence Award in 2023. This allowed the establishment of the Primary Aldosteronism Centre of Research Excellence (PACE), bringing together world-class researchers from Hudson Institute, <a href=\"https:\/\/monashhealth.org\/\">Monash Health<\/a>, Monash University, University of Queensland Diamantina Institute, Baker Heart and Diabetes Institute, Curtin University, University of Western Australia and Menzies School of Health.<\/p>\n\n\n\n<p>\u201cThe aim of PACE is to coordinate PA research and develop integrated strategies to enable the medical profession \u2013 from general practitioners to major hospitals \u2013 to better understand, identify and treat this condition,\u201d Prof Fuller said.<\/p>\n\n\n\n    <div class=\"block--read-more-banner flex z-20 text-blue-800 bg-blue-100 border-l-4 border-blue-500 px-5 py-3 mb-5 sm:mb-8 \">\n        <p class=\"text-base text-blue-800\">\n            <strong class=\"text-sm uppercase\">Read more |&nbsp;<\/strong>\n            <a href=\"https:\/\/hudson.org.au\/\/news\/setting-the-pace-primary-aldosteronism-research-boost\/\" class=\"underline hover:text-pink-500\" target=\"\">Setting the PACE \u2013 Primary Aldosteronism research boost<\/a>        <\/p>\n    <\/div>\n\n    \n\n\n<p>The establishment of PACE was one of many highlights in this field throughout 2023.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-the-consep-trial\">The CONSEP Trial<\/h2>\n\n\n\n<p>A\/Prof Yang\u2019s group have also received a Clinical Trials Activity Grant from the Medical Research Future Fund (MRFF) for the <a href=\"https:\/\/hudson.org.au\/research-program\/consep\/\">CONSEP<\/a> (Conn Syndrome Evaluation in Primary Care) trial to be conducted in GP clinics across Victoria, South Australia and Tasmania. CONSEP aims to increase the effectiveness of PA detection by testing a new intervention based on educational outreach and electronic clinical decision support.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-research-highlights\">Research highlights<\/h2>\n\n\n\n<p>Reflecting on PACE\u2019s prominence in the PA research community, 2023 also saw the publication of novel research discoveries from the team, including<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PA affects up to 14 per cent of hypertensive patients<\/li>\n\n\n\n<li>It is cost effective to screen for PA from the onset of hypertension rather than waiting for resistant<br>hypertension to develop<\/li>\n\n\n\n<li>Oral contraceptives can cause a false-positive PA screening test result<\/li>\n\n\n\n<li>PA screening tests can vary within individuals and should be measured at least twice to be certain<\/li>\n\n\n\n<li>Abnormal screening tests for PA are common in both First Nations peoples and non-Indigenous people based in Darwin.<br><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-finding-solutions-for-hypertension-patients-worldwide\">Finding solutions for hypertension patients worldwide<\/h2>\n\n\n\n<p>With PA identified as a major health concern in Australia, not to mention an estimated 1.13 billion hypertension cases worldwide, it\u2019s an area of research that can change lives, and Hudson Institute is leading the way.<\/p>\n\n\n\n<p>\u201cAs a clinician, I do research because I want to answer clinical questions and address challenges beyond the consultation room. While I love being a clinician and helping patients, being able to work on problems identified in the clinic, find solutions and change clinical practice on a larger scale is extremely rewarding.\u201d Associate Professor Jun Yang.<\/p>\n\n\n\n    <div class=\"block--read-more-banner flex z-20 text-blue-800 bg-blue-100 border-l-4 border-blue-500 px-5 py-3 mb-5 sm:mb-8 \">\n        <p class=\"text-base text-blue-800\">\n            <strong class=\"text-sm uppercase\">Read more |&nbsp;<\/strong>\n            <a href=\"https:\/\/hudson.org.au\/\/news\/tackling-hypertension-at-the-source\/\" class=\"underline hover:text-pink-500\" target=\"\">Tackling hypertension at the source<\/a>        <\/p>\n    <\/div>\n\n    \n\n\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile has-background\" style=\"background-color:#19425c;grid-template-columns:46% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"455\" src=\"https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-1024x455.png\" alt=\"\" class=\"wp-image-64162 size-full\" srcset=\"https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-1024x455.png 1024w, https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-300x133.png 300w, https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-768x341.png 768w, https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-1536x683.png 1536w, https:\/\/hudson.org.au\/wp-content\/uploads\/2024\/06\/Annual-Report-2023-Cover-Web-4-2048x911.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<h3 class=\"wp-block-heading has-text-align-center has-white-color has-text-color\" id=\"h-read-more-stories-like-this-in-the-2023-annual-report\">Read more stories like this in the<br>2023 Annual Report<\/h3>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-50 has-custom-font-size has-medium-font-size\"><a class=\"wp-block-button__link has-white-color has-text-color has-background wp-element-button\" href=\"https:\/\/hudson.org.au\/about\/annual-reports\/\" style=\"border-radius:54px;background-color:#ed0a72\"><strong>READ MORE<\/strong><\/a><\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The establishment of the Primary Aldosteronism Centre of Research Excellence (PACE), brings together world-class researchers to improve the diagnosis of primary aldosteronism (PA)&hellip;&nbsp;&nbsp;<a class=\"read-more\" href=\"https:\/\/hudson.org.au\/news\/setting-a-new-pace-for-hypertension\/\">Read more<\/a><\/p>\n","protected":false},"featured_media":64451,"menu_order":0,"template":"","issue":[],"tag":[],"story-type":[87,85],"treatment-type":[],"class_list":["post-64447","hdsn_news_post","type-hdsn_news_post","status-publish","has-post-thumbnail","hentry","story-type-award","story-type-discovery"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Setting a new PACE for hypertension<\/title>\n<meta name=\"description\" content=\"Primary Aldosteronism (PA) affects 10% of hypertension patients, The PA Centre of Research Excellence is improving diagnosis and treatment.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hudson.org.au\/news\/setting-a-new-pace-for-hypertension\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta 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