{"id":60955,"date":"2024-03-14T13:55:34","date_gmt":"2024-03-14T02:55:34","guid":{"rendered":"https:\/\/hudson.org.au?post_type=hdsn_news_post&p=60955"},"modified":"2025-12-03T11:55:41","modified_gmt":"2025-12-03T00:55:41","slug":"pelvic-organ-prolapse-cure-comes-closer","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/pelvic-organ-prolapse-cure-comes-closer\/","title":{"rendered":"Pelvic organ prolapse cure closer"},"content":{"rendered":"\n

New ways to prevent and cure pelvic organ prolapse<\/a> (POP) are a big step closer, thanks to major funding for pioneering research at Hudson Institute.<\/p>\n\n\n\n

Two world-leading projects have been recognised by the Medical Research Future Fund (MRFF) for their potential to impact this debilitating condition.<\/p>\n\n\n\n

Hudson\u2019s own POP specialists, Dr Shayanti Mukherjee<\/a>, Professor Jerome Werkmeister<\/a> and Professor Caroline Gargett<\/a>, with lead researcher, Associate P<\/a>rofessor Anna Rosamilia<\/a>, Head of the Pelvic Floor Unit at Monash Health, to receive an MRFF – Clinician Researchers: Applied Research in Health grant totalling nearly $1.4 million over four years.<\/p>\n\n\n\n

Prevention and cure of pelvic organ prolapse<\/h2>\n\n\n\n

Their project aims to transform the field of female pelvic floor health on two fronts: prevention and cure of POP.<\/p>\n\n\n\n

POP is a common condition that affects many women, soon after or many years after vaginal birth. It occurs when the muscles and tissues that support the pelvic organs become weak or damaged, causing the organs to drop or press against the walls of the vagina.<\/p>\n\n\n

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L-R: Dr Saeedeh Darzi, Dr Kallyanashis Paul, Dr Shayanti Mukherjee<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n

They propose that 3D printed (3DP) grafts can improve pelvic reconstructive surgery outcomes and nanostructured hydrogels can reverse birth induced injury and prevent POP in the future, using 3D printing, nanotechnology and cellular bioprinting to advance Australian health outcomes, practice and policy.<\/p>\n\n\n\n

A key to their research is the use of 3D printing, nanotechnology and cellular bioprinting in POP surgery, which is where the other award recipient, Dr Kallyanashis Paul<\/a>, comes in.<\/p>\n\n\n\n

He has received an MRFF Early to Mid-Career Researchers Grant worth $800,000 over two years for his project on 3D bioprinted strategies for improving female pelvic reconstructive surgery outcomes.<\/p>\n\n\n\n

His research proposes a paradigm shift in pelvic reconstructive practice by introducing absorbable 3D bioprinted grafts boosted with a patient\u2019s own cells, aiming to drastically reduce the post-surgical immune response and prevent adverse reactions.<\/p>\n\n\n\n

Dr Paul will be testing a range of different designs and those found to work best will undergo further testing by A\/Prof Rosamilia and her team.<\/p>\n\n\n\n

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\n Read more | <\/strong>\n Pelvic organ prolapse prevention and cure<\/a>, Natural mesh provides hope for pelvic organ prolapse<\/a> <\/p>\n <\/div>\n\n \n\n\n

What causes pelvic organ prolapse?<\/h2>\n\n\n\n

There are several factors that can contribute to the development of pelvic organ prolapse. These include<\/p>\n\n\n\n