{"id":55982,"date":"2023-05-11T16:50:04","date_gmt":"2023-05-11T06:50:04","guid":{"rendered":"https:\/\/hudsonorgau.wpengine.com\/?post_type=hdsn_news_post&#038;p=55982"},"modified":"2024-11-12T11:22:59","modified_gmt":"2024-11-12T00:22:59","slug":"surviving-childhood-cancer-lucas-story","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/surviving-childhood-cancer-lucas-story\/","title":{"rendered":"Surviving childhood cancer &#8211; Luca&#8217;s story"},"content":{"rendered":"\n    <div class=\"block--callout flex z-20 text-blue-800 bg-gray-100 p-6 mb-5 sm:mb-8 sm:float-right sm:w-1\/2 sm:ml-6\">\n        <div class=\"cms-content\">\n            <h2 id=\"childhood-cancer-facts-source-cci\"><strong>Childhood cancer facts (Source: CCI)<\/strong><\/h2>\n<ul>\n<li>One in five children diagnosed with cancer will not survive.<\/li>\n<li>Most survivors will suffer long-term disability from the toxic treatments.<\/li>\n<li>Cancer remains the leading disease-related cause of death among Australian children.<\/li>\n<li>Despite many years of research, survival rates from some cancers have hardly improved.<\/li>\n<li>In the last four decades, 500 drugs for adult cancers were approved in the US, but only 12 were approved to treat childhood cancers.<\/li>\n<li>Cancer kills three children every week in Australia \u2013 more than any other disease.<\/li>\n<\/ul>\n        <\/div>\n    <\/div>\n\n    \n\n\n<p class=\"has-text-color has-medium-font-size\" style=\"color:#19425c\">It\u2019s hard to imagine four words more frightening to a parent than \u201cYour child has cancer\u201d.  Monique and Baden share Luca&#8217;s story. <\/p>\n\n\n\n<p>Amid the fear and panic such a sentence creates, three-year-old Luca\u2019s parents, Monique and Baden, had little choice but to trust in the best that medical science could offer.<\/p>\n\n\n\n<p>To treat the \u201cmass\u201d that a CT scan showed in his brain, Luca needed surgery.<\/p>\n\n\n\n<p>Monique and Baden did not know whether Luca would survive, or how he might be affected if he did &#8211; and that was just the start of their cancer journey.<\/p>\n\n\n\n<p>\u201cIt turned out to be a high-grade glioblastoma \u2013 one of the rarest and most dangerous types of brain tumour,\u201d Monique said. \u201cBut the surgeons were confident they had removed it all.<\/p>\n\n\n\n<p>\u201cBecause it\u2019s so rare they couldn\u2019t say \u2018this is what we do with this type of tumour\u2019 so we threw everything at it.\u201d<\/p>\n\n\n\n<p>What followed was 11 rounds of chemotherapy over the next 10 months, then 33 consecutive days of radiotherapy.<\/p>\n\n\n\n<p>That was Luca&#8217;s story five years ago. Today Luca is a healthy, cheeky eight-year-old who is indirectly increasing the survival hopes of the next child with a glioblastoma.<\/p>\n\n\n\n<p>Because Monique and Baden agreed to donate tissue samples from Luca\u2019s tumour for research, those cells are still being used to test potential treatments.<\/p>\n\n\n\n<p>That\u2019s where Hudson Institute comes in.<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" id=\"h-luca-s-tumour-sample-is-saving-other-children-s-lives\" style=\"color:#19425c\">Luca&#8217;s tumour sample is saving other children&#8217;s lives<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute.jpg\" alt=\"Professor Ron Firestein and Dr Jason Cain work at Hudson Institute is helping children like Luca - childhood cancer survivor\" class=\"wp-image-55989\" srcset=\"https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute.jpg 600w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute-300x300.jpg 300w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute-150x150.jpg 150w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute-320x320.jpg 320w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Professor-Ron-Firestein-and-Dr-Jason-Cain-in-their-lab-at-Hudson-Institute-400x400.jpg 400w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><figcaption class=\"wp-element-caption\"><em>Professor Ron Firestein and Dr Jason Cain <\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>As home to the<a href=\"https:\/\/hudson.org.au\/ccma\/\" target=\"_blank\" rel=\"noreferrer noopener\"> Childhood Cancer Model Atlas (CCMA) <\/a>\u2013 a tissue bank where samples of actual cancers can be stored and reproduced \u2013 Hudson Institute is a global hub for paediatric cancer research.<\/p>\n\n\n\n<p>Head of Hudson Institute&#8217;s Centre for Cancer Research, Professor Ron Firestein, says the CCMA is a goldmine for cancer researchers everywhere.<\/p>\n\n\n\n<p>\u201cChildren\u2019s cancers make up only about one per cent of all diagnosed cancers, so the pharmaceutical industry tends not to invest in finding new treatments,\u201d Prof Firestein said.<\/p>\n\n\n\n<p>\u201cHaving models (samples) of various childhood cancers allows us to study the disease and understand how it develops, what makes it grow and ultimately what treatments can be used to fight it off and hopefully cure it.\u201d<\/p>\n\n\n\n<p>The CCMA is the world\u2019s biggest living biobank of paediatric tumour tissue samples, and the data from the tests we run on all of them is freely available to every paediatric&nbsp;oncologist and childhood&nbsp;cancer researcher worldwide.<\/p>\n\n\n\n<p>That means every child like Luca, regardless of their own outcome, can help save lives through the use of their tumour tissue.<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-color\" style=\"color:#19425c\" class=\"wp-block-heading has-text-color\" style=\"color:#19425c\" id=\"helping-families-through-treatment\">Helping families through treatment<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab-300x300.jpg\" alt=\"Postdoctoral Researchers Dr Paul Daniel and Dr Claire Sun who work in childhood cancer at Hudson Institute\" class=\"wp-image-55990\" srcset=\"https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab-300x300.jpg 300w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab-150x150.jpg 150w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab-320x320.jpg 320w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab-400x400.jpg 400w, https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/04\/Postdoctoral-Researchers-Dr-Paul-Daniel-and-Dr-Claire-Sun-in-their-lab.jpg 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption class=\"wp-element-caption\"><em>Dr Paul Daniel and Dr Claire Sun<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n<p>The CCMA is the outcome of seven years of support and more than $7 million in funding from the <a href=\"https:\/\/www.childrenscancerfoundation.com.au\/\">Children&#8217;s Cancer Foundation<\/a>. It was developed through active collaborations with 34 cancer research institutes, including Stanford University (USA), the University of California San Francisco (USA), The Hospital for Sick Children (Canada), Johns Hopkins University (USA), McGill University (Canada), the Institute of Cancer Research (UK), and Hopp Children&#8217;s Cancer Center Heidelberg (Germany). The CCMA also benefited from the support of the Australian Government\u2019s <a href=\"https:\/\/www.health.gov.au\/our-work\/medical-research-future-fund\">Medical Research Future Fund<\/a> and the <a href=\"https:\/\/rcdfoundation.org\/\">Robert Connor Dawes Foundation<\/a>.<\/p>\n\n\n\n<p>Assistant Professor of Paediatrics at Harvard Medical School, Dr Mimi Bandopadhayay, says the CCMA is essential to help identify new treatments. \u201cThis work is a tour de force that includes the largest collection of brain tumour models, generating a resource that will be invaluable to researchers across the world,\u201d she said.<\/p>\n\n\n\n<p>And it\u2019s not just about saving lives, as Hudson\u2019s Dr Jason Cain explains. \u201cMany survivors of childhood cancer are left with debilitating long-term side effects of their treatments. We need to do better,\u201d he said.<\/p>\n\n\n\n<p>The team\u2019s goal is to determine which patients are likely to respond to which therapies, avoiding ineffective treatments (and their side effects).<\/p>\n\n\n\n<p>\u201cNo one treatment is going to be effective for all patients, even with the same cancer diagnosis, so we aim to identify several different therapies that can be used in combination to treat patients,\u201d Dr Cain said.<\/p>\n\n\n\n<p>Luca\u2019s mother, Monique, agrees. \u201cI\u2019d hope that through this work, the next family gets a clearer picture of the available treatments and what can be done.\u201d<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><a href=\"https:\/\/hudson.org.au\/\/newsletters\/issues\/\">VIEW HUDSON NEWS WINTER 2023<\/a><\/p>\n\n\n\n            <div class=\"block-impact max-w-screen bg-white \">\n                <div class=\"relative z-10 py-12\">\n                    <div class=\"hn-container w-full mx-auto px-3 md:px-7 xl:px-11 block\">\n                        <div class=\"relative mb-4\">\n                            <h2 class=\"font-bold text-2xl md:text-3xl text-blue-800 text-center\" class=\"font-bold text-2xl md:text-3xl text-blue-800 text-center\" id=\"hudson-news-winter-2023\">Hudson News Winter 2023<\/h2>\n                        <\/div>\n                        <div class=\"slick-slider slick-slider--impact flex relative w-full max-w-full\">\n                            \n                                <a href=\"https:\/\/hudson.org.au\/news\/hudson-news-winter-2023\/\" class=\"group relative flex flex-col w-1\/5 h-full bg-white mx-1 hover:bg-pink-500 transition duration-200\">\n                                    <div class=\"relative w-full flex-shrink-0 bg-gray-800 bg-cover bg-center h-0\" style=\"padding-top: 100%; 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background-image: url('https:\/\/hudson.org.au\/wp-content\/uploads\/2023\/05\/Luca-Hall-Boggia-400x400.jpg')\">\n                                                                            <\/div>\n                                    <div class=\"relative h-full p-4 pb-8\">\n                                        <time datetime=\"2023-05-11\" class=\"block text-sm leading-tight mb-1 group-hover:text-white\">11 May 2023<\/time>\n                                        <h3 class=\"text-xl text-blue-700 font-bold leading-tight mb-6 group-hover:text-white\" style=\"margin-top: 0; margin-bottom: 1.5rem;\" class=\"text-xl text-blue-700 font-bold leading-tight mb-6 group-hover:text-white\" style=\"margin-top: 0; margin-bottom: 1.5rem;\" id=\"surviving-rare-childhood-brain-cancers\">Surviving rare childhood brain cancers<\/h3>\n                                        <svg class=\"absolute w-3 h-auto fill-current text-pink-500 group-hover:text-white\" style=\"left: 1rem; bottom: 1rem;\" viewBox=\"0 0 11 17.4\" xml:space=\"preserve\">\n                                            <g>\n                                                <path d=\"M1,17.4c-0.3,0-0.5-0.1-0.7-0.3c-0.4-0.4-0.3-1,0.1-1.4l7.7-7l-7.7-7c-0.4-0.4-0.4-1-0.1-1.4\n                                                    c0.4-0.4,1-0.4,1.4-0.1L11,8.7l-9.4,8.4C1.5,17.3,1.2,17.4,1,17.4z\"\/>\n                                            <\/g>\n                                        <\/svg>\n                                    <\/div>\n                                <\/a>\n                                                        <\/div>\n                    <\/div>\n                <\/div>\n            <\/div>\n            ","protected":false},"excerpt":{"rendered":"<p>It\u2019s hard to imagine four words more frightening to a parent than \u201cYour child has cancer\u201d. Amid the fear and panic such a sentence creates, three-year-old Luca\u2019s parents, Monique and Baden, had little choice but to trust in the best that medical science could offer.&hellip;&nbsp;&nbsp;<a class=\"read-more\" href=\"https:\/\/hudson.org.au\/news\/surviving-childhood-cancer-lucas-story\/\">Read more<\/a><\/p>\n","protected":false},"featured_media":55984,"menu_order":0,"template":"","issue":[158],"tag":[],"story-type":[85],"treatment-type":[93],"class_list":["post-55982","hdsn_news_post","type-hdsn_news_post","status-publish","has-post-thumbnail","hentry","issue-winter-2023","story-type-discovery","treatment-type-precision-medicine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Surviving childhood cancer - Luca&#039;s story | Hudson Institute<\/title>\n<meta name=\"description\" content=\"It\u2019s hard to imagine four words more frightening to a parent than \u201cYour child has cancer\u201d. 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