{"id":55527,"date":"2023-04-05T14:43:01","date_gmt":"2023-04-05T04:43:01","guid":{"rendered":"https:\/\/hudsonorgau.wpengine.com\/?post_type=hdsn_news_post&p=55527"},"modified":"2025-06-30T12:39:56","modified_gmt":"2025-06-30T02:39:56","slug":"new-therapy-gives-important-flu-treatment-option","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/new-therapy-gives-important-flu-treatment-option\/","title":{"rendered":"New therapy gives important flu treatment option"},"content":{"rendered":"\n

The discovery of a new class of host-targeted therapy could give the medical profession a much-needed new flu treatment option for serious infections.<\/p>\n\n\n\n

A pre-clinical study at Hudson Institute of Medical Research has identified a new class of compounds, derived from a protein that naturally exists in our body which, when inhaled, limit the ability of influenza<\/a> virus to replicate in the lung, and protect against damaging inflammation.<\/p>\n\n\n\n

Associate Professor Michelle Tate<\/a> led a team from Hudson Institute and Melbourne-based Lateral Pharma Pty Ltd, whose findings have been published in the journal Clinical & Translational Immunology<\/em><\/a>.<\/p>\n\n\n\n

\u201cThe human body uses inflammation in many positive ways, to keep us healthy,\u201d A\/Prof Tate said. \u201cBut when inflammation goes into overdrive it can get out of control and cause enormous damage, particularly to delicate organs such as the lungs.\u201d<\/p>\n\n\n\n

No current treatments for severe flu<\/h2>\n\n\n\n

There are currently no effective treatments available for severe influenza virus infection. Each year in Australia, influenza infection results in hundreds of deaths and thousands of hospitalisations.<\/p>\n\n\n\n

\u201cUnlike current antiviral influenza drugs, which target the virus itself, these compounds act directly on the cells in the lung.\u201d she said.<\/p>\n\n\n\n

As the therapeutic acts directly on the host cells, it is less likely that influenza virus variants will develop resistance to this treatment. An extra bonus is that this new therapy is naturally derived from a protein our body makes.<\/p>\n\n\n\n

Treatment fine-tunes inflammatory response<\/h2>\n\n\n\n

\u201cThe search is always on for treatment options that can fine-tune the inflammatory response, to strike a balance between inflammation which can be protective or damaging.\u201d A\/Prof Tate said.<\/p>\n\n\n\n

COVID-19 has shown us the damage that can be done by out-of-control inflammation, and A\/Prof Tate says it\u2019s a similar story for flu.<\/p>\n\n\n\n

\u201cWe urgently need new drugs for influenza and emerging respiratory viruses. These results support the potential for Lateral\u2019s novel compounds to help patients with severe respiratory disease,\u201d Lateral Pharma said.<\/p>\n","protected":false},"excerpt":{"rendered":"

The discovery of a new class of host-targeted therapy could give the medical profession a much-needed treatment option for serious flu infections.…  Read more<\/a><\/p>\n","protected":false},"featured_media":55538,"menu_order":0,"template":"","issue":[],"tag":[135],"story-type":[85],"treatment-type":[94],"class_list":["post-55527","hdsn_news_post","type-hdsn_news_post","status-publish","has-post-thumbnail","hentry","tag-business-development","story-type-discovery","treatment-type-immunotherapies"],"acf":[],"yoast_head":"\nNew therapy gives important flu treatment option | Hudson Institute<\/title>\n<meta name=\"description\" content=\"Much-needed new treatment option for serious flu infections after the discovery of a new class of host-targeted therapy.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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