{"id":54931,"date":"2023-03-15T06:00:51","date_gmt":"2023-03-14T19:00:51","guid":{"rendered":"https:\/\/hudsonorgau.wpengine.com\/?post_type=hdsn_news_post&p=54931"},"modified":"2024-08-05T09:55:48","modified_gmt":"2024-08-04T23:55:48","slug":"lymphoma-treatment-targets-multiple-diseases","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/lymphoma-treatment-targets-multiple-diseases\/","title":{"rendered":"Lymphoma treatment targets multiple diseases"},"content":{"rendered":"\n

The search for new therapies to treat a rare type of non-Hodgkins lymphoma has had an unexpected success \u2013 identifying a potential molecular target to treat other related forms of lymphoma as well.<\/p>\n\n\n

\n
\"Dr
Dr Christy Ying<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n

Professor Richard Ferrero<\/a>, Dr Le (Christy) Ying and an international team focussed on finding new treatment options for a form of non-Hodgkins lymphoma that develops in the stomach and is linked to infection by the bacterium, Helicobacter pylori<\/em>.<\/p>\n\n\n\n

They developed a pre-clinical model to study the development of stomach lymphoma associated with H. pylori<\/em> infection, with their findings now being published in The Journal of Pathology<\/a><\/em>.<\/p>\n\n\n\n

Other lymphoma treatment targets<\/h2>\n\n\n\n

\u201cWe believe this treatment may also be used for other related lymphomas that develop outside of the lymphatic system and for which the causes are unknown,\u201d said Professor Ferrero.<\/p>\n\n\n\n

\u201cUsing an antibody to block a key communication node between blood cells known as B and T cells, we showed that we could prevent the development of the precursor lesions leading to stomach lymphoma,\u201d Dr Ying added.<\/p>\n\n\n\n

\u201cBut while it was known that interactions between B and T cells are important for the development of stomach lymphoma in humans, we were the first to show in a pre-clinical model that drugs blocking these interactions may be used to treat this cancer<\/a>,\u201d she said.<\/p>\n\n\n

\n
\"Image<\/a>
Tissue section from a pre-clinical model in which precancerous lesions of stomach lymphoma are seen to be predominantly composed of B cells (green) and surrounded by different types of immune cells (red, yellow).<\/em><\/figcaption><\/figure>\n<\/div>\n\n\n
<\/div>\n","protected":false},"excerpt":{"rendered":"

The search for new therapies to treat a rare type of non-Hodgkins lymphoma has had an unexpected success \u2013 identifying a potential molecular target to treat other related forms of lymphoma as well.…  Read more<\/a><\/p>\n","protected":false},"featured_media":54942,"menu_order":0,"template":"","issue":[],"tag":[],"story-type":[85],"treatment-type":[93],"class_list":["post-54931","hdsn_news_post","type-hdsn_news_post","status-publish","has-post-thumbnail","hentry","story-type-discovery","treatment-type-precision-medicine"],"acf":[],"yoast_head":"\nLymphoma treatment targets multiple diseases | Hudson Institute<\/title>\n<meta name=\"description\" content=\"The search for a new non-Hodgkins Lymphoma treatment has had an unexpected success \u2013 identifying a candidate to treat other lymphoma forms.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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