{"id":43999,"date":"2021-11-29T13:19:22","date_gmt":"2021-11-29T02:19:22","guid":{"rendered":"https:\/\/hudson.org.au?post_type=hdsn_news_post&#038;p=43999"},"modified":"2024-07-08T10:51:27","modified_gmt":"2024-07-08T00:51:27","slug":"small-cell-lung-cancer","status":"publish","type":"hdsn_news_post","link":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/","title":{"rendered":"Combatting a killer &#8211; understanding what causes small cell lung cancer"},"content":{"rendered":"\n<p class=\"has-medium-font-size\">A new understanding of the causes of <a href=\"https:\/\/hudson.org.au\/research-group\/stat-cancer-biology\/\">small cell lung cancer (SCLC)<\/a> could lead to more personalised treatments and lower mortality from this deadly disease.<\/p>\n\n\n\n<p>In a study published in <a href=\"https:\/\/www.nature.com\/articles\/s41388-021-02070-3\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Oncogene<\/em><\/a> researchers at Hudson Institute led by <a href=\"https:\/\/hudson.org.au\/researcher-profile\/daniel-gough\/\">Dr Daniel Gough<\/a> have shown that small cell lung cancer can show significant differences depending on the type of cell it originated in.<\/p>\n\n\n\n<p>According to Dr Gough, that suggests small cell lung cancer is a series of diseases rather than being a single form of cancer \u2013 and that opens up new options for more personalised treatments.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" class=\"wp-block-heading\" id=\"understanding-diversity-key-to-new-therapies\"><strong>Understanding <\/strong>diversity key to new therapies<\/h3>\n\n\n\n<p>Dr Gough said the lung is comprised of a diverse array of cell types and small cell lung cancer was thought to specifically occur in just one &#8211; the rare neuroendocrine cells (PNEC).<\/p>\n\n\n\n<p>\u201cOur study reveals that mutation of the common cancer gene MYC enables other lung cell types to form SCLC,\u201d he said.<\/p>\n\n\n\n<p>\u201cCurrently the survival rate from SCLC is extremely low, so understanding the diversity in causes of small cell lung cancer is key to designing new therapeutic strategies that will improve the lives of these patients.\u201d<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" class=\"wp-block-heading\" id=\"small-cell-lung-cancer-new-therapies\">Small cell lung cancer &#8211; new therapies<\/h3>\n\n\n\n<p>Understanding the cause and drivers of small cell lung cancer complexity will enable the development of new and effective therapies for a disease that is currently a death sentence.<\/p>\n\n\n\n<p>In a hopeful sign for SCLC patients, Dr Gough said: \u201cThis opens up the possibility for personalised medicine based on specific vulnerabilities.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new understanding of the causes of small cell lung cancer (SCLC) could lead to more personalised treatments and lower mortality from this deadly disease.&hellip;&nbsp;&nbsp;<a class=\"read-more\" href=\"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/\">Read more<\/a><\/p>\n","protected":false},"featured_media":43981,"menu_order":0,"template":"","issue":[],"tag":[],"story-type":[],"treatment-type":[],"class_list":["post-43999","hdsn_news_post","type-hdsn_news_post","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Combatting a killer - understanding what causes small cell lung cancer - Hudson Institute of Medical Research<\/title>\n<meta name=\"description\" content=\"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Combatting a killer - understanding what causes small cell lung cancer\" \/>\n<meta property=\"og:description\" content=\"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Hudson Institute of Medical Research\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-08T00:51:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/hudson.org.au\/wp-content\/uploads\/2021\/11\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"999\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/\",\"url\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/\",\"name\":\"Combatting a killer - understanding what causes small cell lung cancer - Hudson Institute of Medical Research\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/hudson.org.au\\\/wp-content\\\/uploads\\\/2021\\\/11\\\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg\",\"datePublished\":\"2021-11-29T02:19:22+00:00\",\"dateModified\":\"2024-07-08T00:51:27+00:00\",\"description\":\"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/#breadcrumb\"},\"inLanguage\":\"en-AU\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-AU\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/#primaryimage\",\"url\":\"https:\\\/\\\/hudson.org.au\\\/wp-content\\\/uploads\\\/2021\\\/11\\\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg\",\"contentUrl\":\"https:\\\/\\\/hudson.org.au\\\/wp-content\\\/uploads\\\/2021\\\/11\\\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg\",\"width\":1000,\"height\":999,\"caption\":\"Dr Dan Gough\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/small-cell-lung-cancer\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/hudson.org.au\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"News\",\"item\":\"https:\\\/\\\/hudson.org.au\\\/news\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Combatting a killer &#8211; understanding what causes small cell lung cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#website\",\"url\":\"https:\\\/\\\/hudson.org.au\\\/\",\"name\":\"Hudson Institute of Medical Research\",\"description\":\"Transforming lives through scientific discovery.\",\"publisher\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/hudson.org.au\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-AU\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#organization\",\"name\":\"Hudson Institute of Medical Research\",\"url\":\"https:\\\/\\\/hudson.org.au\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-AU\",\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/hudson.org.au\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/hudson-logo-1.jpg\",\"contentUrl\":\"https:\\\/\\\/hudson.org.au\\\/wp-content\\\/uploads\\\/2017\\\/05\\\/hudson-logo-1.jpg\",\"width\":1200,\"height\":316,\"caption\":\"Hudson Institute of Medical Research\"},\"image\":{\"@id\":\"https:\\\/\\\/hudson.org.au\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Combatting a killer - understanding what causes small cell lung cancer - Hudson Institute of Medical Research","description":"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Combatting a killer - understanding what causes small cell lung cancer","og_description":"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.","og_url":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/","og_site_name":"Hudson Institute of Medical Research","article_modified_time":"2024-07-08T00:51:27+00:00","og_image":[{"width":1000,"height":999,"url":"https:\/\/hudson.org.au\/wp-content\/uploads\/2021\/11\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/","url":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/","name":"Combatting a killer - understanding what causes small cell lung cancer - Hudson Institute of Medical Research","isPartOf":{"@id":"https:\/\/hudson.org.au\/#website"},"primaryImageOfPage":{"@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/#primaryimage"},"image":{"@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/hudson.org.au\/wp-content\/uploads\/2021\/11\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg","datePublished":"2021-11-29T02:19:22+00:00","dateModified":"2024-07-08T00:51:27+00:00","description":"New research into the causes of small cell lung cancer shows it is several diseases - opening the door to more personalised treatments.","breadcrumb":{"@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/#breadcrumb"},"inLanguage":"en-AU","potentialAction":[{"@type":"ReadAction","target":["https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-AU","@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/#primaryimage","url":"https:\/\/hudson.org.au\/wp-content\/uploads\/2021\/11\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg","contentUrl":"https:\/\/hudson.org.au\/wp-content\/uploads\/2021\/11\/Dr-Dan-Gough-News-story-scaled-e1649770480988.jpg","width":1000,"height":999,"caption":"Dr Dan Gough"},{"@type":"BreadcrumbList","@id":"https:\/\/hudson.org.au\/news\/small-cell-lung-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/hudson.org.au\/"},{"@type":"ListItem","position":2,"name":"News","item":"https:\/\/hudson.org.au\/news\/"},{"@type":"ListItem","position":3,"name":"Combatting a killer &#8211; understanding what causes small cell lung cancer"}]},{"@type":"WebSite","@id":"https:\/\/hudson.org.au\/#website","url":"https:\/\/hudson.org.au\/","name":"Hudson Institute of Medical Research","description":"Transforming lives through scientific discovery.","publisher":{"@id":"https:\/\/hudson.org.au\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/hudson.org.au\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-AU"},{"@type":"Organization","@id":"https:\/\/hudson.org.au\/#organization","name":"Hudson Institute of Medical Research","url":"https:\/\/hudson.org.au\/","logo":{"@type":"ImageObject","inLanguage":"en-AU","@id":"https:\/\/hudson.org.au\/#\/schema\/logo\/image\/","url":"https:\/\/hudson.org.au\/wp-content\/uploads\/2017\/05\/hudson-logo-1.jpg","contentUrl":"https:\/\/hudson.org.au\/wp-content\/uploads\/2017\/05\/hudson-logo-1.jpg","width":1200,"height":316,"caption":"Hudson Institute of Medical Research"},"image":{"@id":"https:\/\/hudson.org.au\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/hdsn_news_post\/43999","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/hdsn_news_post"}],"about":[{"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/types\/hdsn_news_post"}],"version-history":[{"count":0,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/hdsn_news_post\/43999\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/media\/43981"}],"wp:attachment":[{"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/media?parent=43999"}],"wp:term":[{"taxonomy":"issue","embeddable":true,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/issue?post=43999"},{"taxonomy":"tag","embeddable":true,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/tag?post=43999"},{"taxonomy":"story-type","embeddable":true,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/story-type?post=43999"},{"taxonomy":"treatment-type","embeddable":true,"href":"https:\/\/hudson.org.au\/wp-json\/wp\/v2\/treatment-type?post=43999"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}